Preoperative Prehabilitation for Sarcopenic Patients Prior to Pancreatic Surgery for Cancer
Prehabilitaion Program for Sarcopenic Patients Prior to Pancreaticoduodenectomy for Periampullary Malignant Tumors
University Hospital, Lille
158 participants
May 17, 2022
INTERVENTIONAL
Conditions
Summary
Major digestive surgery is associated with a significant rate of postoperative complications. To improve postoperative outcome, efforts are focused on postoperative course leading to the concept of rehabilitation. However, the rehabilitation concept does not allow to improve muscular and functional reserves at the time of surgery. Sarcopenia is a condition characterized by loss of skeletal muscle mass and function. Also, the prevalence of sarcopenia in patients with cancer is high and has a prevalence of around 25% in patients with pancreatic cancer, with a considerable impact on postoperative and survival outcomes. The hypothesis is the preoperative management of sarcopenia by a rehabilitation program could improve patients' operative outcomes by reducing the rate of postoperative complications.
Eligibility
Plain Language Summary
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Interventions
4-week trimodal prehabilitation program: Exercise, nutritional supplementation, and psychological support
perioperative immunonutrition by ORAL IMPACT
Locations(1)
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NCT04469504