Effect of Thickened Feeds on Clinical Outcomes in Children With Brief Resolved Unexplained Event

This study follows infants who experienced a Brief Resolved Unexplained Event (BRUE) — a sudden and frightening episode involving choking, color change, limpness, or breathing difficulty — to see whether thickening their feeds reduces future episodes and healthcare use. BRUEs are common in infancy but poorly understood, and swallowing difficulties may play a role. Infants under 1 year of age who are admitted to Boston Children's Hospital after their first-ever BRUE may be eligible, unless they have a pre-existing condition such as a seizure disorder or congenital heart disease. Participation involves following the infant's feeding and health outcomes over 1 year, with some infants receiving thickened feeds and others receiving standard feeding. This summary was generated with AI assistance to help patients understand the study in plain language.