Personalized Autologous Transplant for Multiple Myeloma

This study tests personalized approaches to stem cell transplants (using the patient's own stem cells) for people with multiple myeloma — a cancer of plasma cells in the bone marrow. It aims to tailor the high-dose chemotherapy dose based on individual patient factors to improve safety and outcomes. **You may be eligible if...** - You have been diagnosed with multiple myeloma or a related plasma cell disorder that requires treatment - You have received at least 2 prior lines of therapy - Your kidney function meets the minimum required level - Your doctor has determined you are a candidate for an autologous (your own cells) stem cell transplant **You may NOT be eligible if...** - You have not yet received prior treatment - Your kidney function is too low to safely receive high-dose chemotherapy - You have other conditions that make transplant unsafe Talk to your doctor to see if this trial is right for you.