RecruitingNot ApplicableNCT04506853

Single-Sided Deafness and Asymmetric Hearing Loss

Single-Sided Deafness and Asymmetric Hearing Loss Post-Approval Study


Sponsor

Med-El Corporation

Enrollment

65 participants

Start Date

Feb 22, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of the study is to evaluate the long-term safety and effectiveness of cochlear implantation of the approved population in adults and children with single-sided deafness and asymmetric hearing loss.


Eligibility

Min Age: 5 Years

Inclusion Criteria7

  • Five years of age or older at the time of implantation
  • Unilateral profound hearing loss, as defined by a pure-tone average (500, 1000, 2000, and 4000 Hz) of 90 dB or greater in the ear to be implanted
  • Sensorineural hearing loss in the ear to be implanted, as defined by an air-bone gap less than or equal to 10 dB at two or more frequencies out of 500, 1000, 2000, and 4000 Hz and a diagnosed pathology of the outer or middle ear
  • Normal hearing or mild to moderate hearing loss in the non-implanted ear, as defined by a pure-tone average (500, 1000, 2000, and 4000 Hz) of 55 dB or less
  • Word recognition in the ear to be implanted of 5% or less on CNC word score in quiet
  • Previous experience with an appropriately-fit Contralateral Routing of Signal (CROS) hearing aid, BI-Contralateral Routing of Signal (CROS) hearing aid, bone conduction, or traditional hearing aid, as deemed appropriate by investigator
  • Fluent in English

Exclusion Criteria7

  • Duration of profound hearing loss of 10 years or more
  • Absence of cochlear development or non-functionality of cochlear nerve
  • Other retrocochlear hearing loss
  • Evidence of severe cochlear malformation (i.e., common cavity or ossification)
  • External or middle ear infection
  • Suspected developmental or cognitive concern
  • Other medical contraindication for surgery or anesthesia

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Interventions

DEVICEMED-EL Cochlear Implant System

Cochlear implant and audio processor


Locations(6)

Ann & Robert H. Lurie Children's Hospital of Chicago

Chicago, Illinois, United States

University of Iowa

Iowa City, Iowa, United States

New York Eye and Ear Infirmary

New York, New York, United States

University of North Carolina

Chapel Hill, North Carolina, United States

Virginia Mason Medical Center

Seattle, Washington, United States

Sunnybrook Health Sciences Center

Toronto, Ontario, Canada

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NCT04506853


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