The Utility of Thromboelastography in Traumatic Brain Injury
The Utility of Thromboelastography for Predicting the Risk of Coagulation-Related Damages Secondary to Traumatic Brain Injury
Shanghai 6th People's Hospital
500 participants
Sep 1, 2018
OBSERVATIONAL
Conditions
Summary
Hemocoagulation disorder is recognized to have crucial effects on hemorrhagic or ischemic diseases. Coagulation-related damages secondary to traumatic brain injury are common and severe secondary insults of head trauma and often leads to a poor prognosis. In this study, we sought to assess if posttraumatic hemocoagulation disorders determined using thromboelastography are associated with coagulation-related damages secondary to traumatic brain injury, and evaluate their influence on outcome among patients with head trauma. Based on above results, prediction models or risk scoring systems will be further developed and validated to predict coagulation-related damages secondary to traumatic brain injury.
Eligibility
Inclusion Criteria2
- Patients who are delivered to hospital within 24 hours after head trauma
- Patients whose abbreviated injury score (AIS) for other body regions is 3 or less are considered to be isolated traumatic brain injury
Exclusion Criteria5
- Patients with existing prior neurological disease
- Patients with known coagulation disorders
- Patients on anticoagulants and medications known to affect coagulation function within 30 days before trauma
- Patients receiving blood components prior to blood draw
- Patients who deteriorate and die before determining whether coagulation- related damage exists
Interested in this trial?
Get notified about updates and connect with the research team.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT04524637