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RecruitingNCT04528446

The Impact of Glomerular Disorders on Bone Quality and Strength

Sponsor

Columbia University

Enrollment

270 participants

Start Date

Jun 14, 2019

Study Type

OBSERVATIONAL

Conditions

Bone FractureBone Diseases, MetabolicGlomerular Disease

Summary

The primary objectives of this study are to: (1) determine the impact of glomerular disease on bone strength and (2) investigate the pathophysiologic underpinnings of impaired bone strength in glomerular disease.

Eligibility

Min Age: 5 YearsMax Age: 55 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Blood draw and Urine collection, Dual-energy X-ray absorptiometry, and others for people with bone diseases, metabolic, bone fracture, and other related conditions. The study is currently recruiting participants at 2 locations. People eligible for this study include aged 5 Years to 55 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

RADIATIONDual-energy X-ray absorptiometry

DXA whole body, hip, spine, and radius at baseline, and 12-month visit.

RADIATIONHigh Resolution Peripheral Quantitative Computed Tomography (HR-pQCT)

HR-pQCT of the radius and tibia at baseline, and 12-month visit.

OTHERBlood draw and Urine collection

The blood draw can be completed +/- 3 weeks from baseline or 12-month visit.

OTHERQuestionnaires

Questionnaires regarding fracture history, physical activity and dietary intake at baseline, and 12-month visit.

Locations(2)

Columbia University Irving Medical Center

New York, New York, United States

The Children's Hospital of Philadelphia

Philadelphia, Pennsylvania, United States

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NCT04528446

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