RecruitingNCT04528511

BurdEn of NEw Onset Atrial FIbrillation in patienTs With Acute Myocardial Infarction

BurdEn of NEw Onset Atrial FIbrillation in patienTs With Acute Myocardial Infarction: the BENEFIT-AMI Multicenter Prospective Registry


Sponsor

Shanghai 10th People's Hospital

Enrollment

774 participants

Start Date

Oct 1, 2020

Study Type

OBSERVATIONAL

Conditions

Summary

To validate the prognostic importance of the burden of new-onset atrial fibrillation (NOAF) complicating acute myocardial infarction (AMI) in a prospectively designed hospital-based registry. To characterize those factors that contribute to the progression of post-MI NOAF burden. To establish a prediction model for the risk stratification of patients with NOAF complicating AMI. To explore the clinical usefulness of NOAF burden in guiding the anticoagulation therapy among patients with post-MI NOAF.


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • Adult patients (\>18 years old);
  • Patient with AMI (including STEMI and NSTEMI) who developed NOAF during the index hospitalization;
  • Patients must have received in-hospital CEM for at least 5 days;
  • Patients must give informed consent.

Exclusion Criteria8

  • Patients with a medical history of pre-existing AF;
  • Patients with a medical history of rheumatic valvular disease;
  • Patients with a medical history of sick sinus syndrome;
  • Patients undergoing emergent coronary artery bypass surgery;
  • Patients who suffer malignant tumors with an expected lifetime less than 1 year ;
  • Patients who refuse to receive CEM during hospitalization and the data of heart rhythm cannot be retrieved;
  • Patients who refuse to receive percutaneous coronary intervention (PCI) or have contraindications for PCI;
  • Patients who have died during the index hospitalization.

Interventions

DEVICEContinuous Electronic Monitor

All patients with NOAF complicating AMI will receive at least 5 days electronic monitoring for the evaluation of NOAF burden


Locations(5)

Kaifeng Central Hospital

Kaifeng, Henan, China

Luoyang Central Hospital

Luoyang, Henan, China

The First Affiliated Hospital of Zhengzhou University

Zhengzhou, Henan, China

Department of Cardiology, Shanghai Tenth People's Hospital

Shanghai, Shanghai Municipality, China

Shanghai Seventh People's Hospital

Shanghai, Shanghai Municipality, China

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NCT04528511


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