DENEX Renal Denervation in Patients With Hypertension on no Antihypertensive Medications

This study is testing a minimally invasive procedure called renal denervation — where nerves around the kidney arteries are deactivated using energy — as a way to lower blood pressure without relying on medication. **You may be eligible if...** - You are between 18 and 80 years old - You either have never taken blood pressure medication (drug-naïve) or are willing to stop taking it for the study period - Your blood pressure is elevated: office systolic reading between 150–180 mmHg, diastolic at least 90 mmHg, and 24-hour monitoring showing systolic readings of 140–170 mmHg - You are willing to have the procedure and follow-up visits **You may NOT be eligible if...** - You have secondary causes of high blood pressure (such as a hormone-secreting tumor) - You have severe kidney disease or only one working kidney - You have had a heart attack or stroke recently - You are pregnant Talk to your doctor to see if this trial is right for you.