Cardiovascular Diseases Clinical Trials

406 recruitingLast updated: June 17, 2026

There are 406 actively recruiting cardiovascular diseases clinical trials across 70 countries. Studies span Not Applicable, Phase 2, Phase 4, Phase 3, Phase 1, Early Phase 1. Top locations include Boston, Massachusetts, United States, New York, New York, United States, Cleveland, Ohio, United States. Updated daily from ClinicalTrials.gov.


Cardiovascular Diseases Trials at a Glance

406 actively recruiting trials for cardiovascular diseases are listed on ClinicalTrialsFinder across 6 cities in 70 countries. The largest study group is Not Applicable with 175 trials, with the heaviest enrollment activity in Boston, New York, and Cleveland. Lead sponsors running cardiovascular diseases studies include University of Alabama at Birmingham, Karolinska Institutet, and Mayo Clinic.

Browse cardiovascular diseases trials by phase

Treatments under study

About Cardiovascular Diseases Clinical Trials

Looking for clinical trials for Cardiovascular Diseases? There are currently 381 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Cardiovascular Diseases trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Cardiovascular Diseases clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 406 trials

Recruiting

Diabetes and Heart Disease Risk in Blacks

ObesityCardiovascular DiseasesHypertension+1 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)2,000 enrolled1 locationNCT00001853
Recruiting
Not Applicable

Moderate-Intensity Statin Plus Ezetimibe in CKD and ASCVD

Cardiovascular DiseasesAtherosclerosisDyslipidemia+2 more
Yonsei University1,952 enrolled1 locationNCT07524101
Recruiting

Biomedical Research Informatics Centre for Cardiovascular Sciences (The BRICCS Study)

Cardiovascular DiseasesCardiovascular Risk Factor
University Hospitals, Leicester9,500 enrolled1 locationNCT04388943
Recruiting

Cardiovascular Disease Progression in Survivors of Community Acquired Pneumonia and Lung Infection by Covid-19.

COVID-19 pneumoniaCardiovascular DiseasesPneumonia, Community-Acquired
Hellenic Institute for the Study of Sepsis650 enrolled18 locationsNCT06601998
Recruiting
Phase 3

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

Cardiovascular DiseasesHypertensionDiabetes Mellitus, Type 2
Boehringer Ingelheim11,800 enrolled1155 locationsNCT07064473
Recruiting
Not Applicable

Effectiveness and Adoption of the TelTex4BP Intervention Among Adults With Hypertension in Nepal

Cardiovascular DiseasesHypertensionBlood Pressure+1 more
Central Department of Public Health500 enrolled2 locationsNCT05979168
Recruiting

100-Year Human Aging Study

Disability PhysicalNeoplasmsCardiovascular Diseases+12 more
Longevity Metrics, Inc.1,000,000 enrolled1 locationNCT07563777
Recruiting

Human Observatory Study

Musculoskeletal DiseaseDisability PhysicalNeoplasms+16 more
Longevity Metrics, Inc.1,000,000 enrolled1 locationNCT07646782
Recruiting
Not Applicable

The PREBEAT Trial: Digital PREhaBilitation in thE Cardiac Surgical populATion

Cardiovascular Diseases
Claire Hines40 enrolled1 locationNCT06983808
Recruiting

Medtronic SYMBIOSIS Post-Market Registry for Patients Undergoing Cardiac Surgery

Cardiovascular Diseases
Medtronic Cardiac Surgery5,000 enrolled14 locationsNCT04241328
Recruiting
Not Applicable

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

Heart FailureCardiovascular DiseasesPulmonary Hypertension+1 more
Abbott Medical Devices850 enrolled68 locationsNCT06526195
Recruiting
Not Applicable

A Digital Lifestyle Intervention in Primary Healthcare to Prevent Cardiovascular Disease

Cardiovascular DiseasesLifestyle Factors
Karolinska Institutet1,000 enrolled6 locationsNCT06847633
Recruiting
Not Applicable

Is Post-exertional Symptom Exacerbation Specific to Patients With Myalgic Encephalomyelitis / Chronic Fatigue Syndrome? A Study Comparing Patients With Myalgic Encephalomyelitis / Chronic Fatigue Syndrome and Patients With Cardiac Diseases Who Underwent an Exercise Test.

Cardiovascular DiseasesFatigue Syndrome, Chronic
Hôpital Européen Marseille80 enrolled1 locationNCT07491315
Recruiting
Phase 4

Treatment With Aspirin After Preeclampsia: TAP Trial

Cardiovascular DiseasesHypertensionPregnancy Complications+8 more
Malamo Countouris60 enrolled1 locationNCT06281665
Recruiting
Phase 4

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

Cardiovascular DiseasesDementiaCognitive Impairment, Mild
Duke University20,000 enrolled103 locationsNCT04262206
Recruiting
Not Applicable

Developing a Brief Intervention to Communicate Cardiovascular Risk to Patients Presenting to the Emergency Department With Chest Pain: a Co-Production Approach. Phase 2.

Cardiovascular Diseases
University of Edinburgh118 enrolled1 locationNCT06903442
Recruiting

Real-life Registry in Patients With Coronary Artery Disease Treated With the SELUTION Sirolimus-eluting Balloon. Selution Iberia Registry

Cardiovascular Diseases
Fundación EPIC960 enrolled6 locationsNCT07256249
Recruiting

Acute and Long-term Cardiovascular Toxicity After Modern Radiotherapy for Breast Cancer

Breast NeoplasmsCardiovascular Diseases
St. Olavs Hospital1,600 enrolled2 locationsNCT02541435
Recruiting
Not Applicable

Brain Connections for Arm Movement After Stroke

Cardiovascular DiseasesCentral Nervous System DiseasesStroke+2 more
VA Office of Research and Development76 enrolled1 locationNCT04286516
Recruiting
Phase 2

Comparative Study on the Mode of Action of Vicadrostat and Spironolactone on Protein Profiles and Renal Hemodynamic Effects (COMPARE-VS)

Heart FailureCardiovascular DiseasesCKD
University Medical Center Groningen100 enrolled2 locationsNCT07304817