RecruitingNCT04536220

Establish Diagnostic Models Based on Portal Venous Blood for Pancreatic Cancer

Establish a Diagnostic Model Based on Multiple Molecule Profiling and Certain Established Markers for Identification of Pancreatic Cancer


Sponsor

Changhai Hospital

Enrollment

300 participants

Start Date

Jan 1, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

Explore new markers based on portal venous blood sampling to establish novel diagnostic models for identification of malignant pancreatic mass.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Inclusion Criteria4

  • age 18-75 years,male or female
  • diagnosis or suspection of solid pancreatic mass based on previous imaging examination (ultrasonography, CT or MRI)
  • lesion diameter larger than 1 cm
  • signed informed consent letter

Exclusion Criteria8

  • pregnant female
  • Pancreatic cystic lesions
  • Anticoagulant/antiplatelet therapy cannot be suspended
  • unable or refuse to provide informed consent
  • Coagulopathy (platelet count < 50× 103/μL,international normalized ratio > 1.5)
  • Severe cardiopulmonary dysfunction that cannot tolerate intravenous anesthesia
  • with history of mental disease
  • other medical conditions that are not suitable for EUS-FNA

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Interventions

DIAGNOSTIC_TESTEndoscopic Ultrasound (EUS), Fine Needle Aspiration

Endoscopic Ultrasound (EUS), Fine Needle Aspiration, which are routine clinical operations


Locations(1)

Changhai Hospital

Shanghai, Shanghai Municipality, China

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NCT04536220


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