RecruitingPhase 1NCT04537403

PET Detection of CCR2 in Human Atherosclerosis


Sponsor

Washington University School of Medicine

Enrollment

100 participants

Start Date

Oct 1, 2020

Study Type

INTERVENTIONAL

Conditions

Summary

: Use of novel radio-pharmaceutical 64CUDOTA-ECL1i to evaluate arterial atherosclrosis


Eligibility

Min Age: 18 YearsMax Age: 89 Years

Inclusion Criteria1

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Exclusion Criteria1

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Interventions

DRUGGroup 1-64CU-DOTA-ECL1i (radioactive imaging medicine)

Patients in Group 1, normal volunteers and patients with carotid and femoral artery disease who will be having surgery, will have a 1 day imaging session lasting approximately 60 minutes with an injection of 64CU-DOTA-ECL1i to visualize the carotid and femoral arteries. Patients with carotid and femoral artery disease will have their plaque specimens collected for further sutdy

DRUGGroup 2 64CU-DOTA-ECL1i (radioactive imaging medicine)

Patients in Group 2, who are patients with carotid and femoral artery disease who will not be having surgery will have two imaging sessions 7-14 days apart


Locations(1)

Washington University CCIR

St Louis, Missouri, United States

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NCT04537403


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