RecruitingNCT04545502

PANTHER Study of Terumo Aortic Knitted and Woven Grafts, and Cardiovascular Patches

A Prospective and Retrospective, Multi-Centre, Post-Market, Non-Interventional Study of Terumo Aortic Knitted and Woven Grafts, and Cardiovascular Patches


Sponsor

Vascutek Ltd.

Enrollment

2,000 participants

Start Date

Feb 17, 2021

Study Type

OBSERVATIONAL

Conditions

Summary

The purpose of this registry is to collect safety and performance data on all commercially available Terumo Aortic knitted and woven grafts, and cardiovascular patches in standard clinical practice. Data will be collected both retrospectively and prospectively.


Eligibility

Min Age: 18 Years

Inclusion Criteria10

  • All Patients:
  • Patient meets the minimum age as per local regulations at time of consent
  • Patient requires treatment with study device(s) according to the IFU(s)
  • Patient is willing and able to comply with all SOC procedures and study visits
  • Patient or their legally authorised representative (LAR) has given written informed consent to participate in study, including consent to collect data retrospectively
  • For prospective emergency patients, retrospective consent is permissible
  • For retrospective patients who are deceased at time of enrollment, local EC regulations relating to consent process should be followed.
  • Retrospective Patients only:
  • Patient has a minimum of 1 year post-operative follow-up data available, or complete data to death.
  • Patient implant date is no more than 5 years prior to study start date.

Exclusion Criteria3

  • Patient is unable or unwilling to comply with the SOC procedures or follow-up regime
  • Patient is contraindicated per the device IFU
  • Patient has any other medical, social or psychological problems that in the opinion of the investigator preclude them from receiving this treatment and the procedures and evaluations pre- and post-procedure

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Interventions

DEVICEGelsoft Plus Vascular Graft

Gelatin coated, knitted vascular prosthesis implanted to act as a conduit for channeling blood during repair of damaged or diseased vessels.

DEVICEVascular Bypass Graft

Gelatin coated, knitted vascular prosthesis implanted to act as an extra-anatomical bypass for channeling blood during repair of damaged or diseased vessels.

DEVICECardiovascular Patch

Cardiovascular knitted polyester patches are frequently used to treat the carotid or femoral arteries to prevent stroke and repair damage to vessels.

DEVICEGelweave Vascular Graft

The Gelweave woven polyester vascular graft allows replacement of large sections of arteries and, following anastomosis to the native blood vessel, provides a stable conduit for blood flow.

DEVICEGelweave Valsalva Vascular Graft

This woven polyester graft is designed to match the aortic root anatomy and is implanted to repair or replace a portion of the aorta in case of an aneurysm, dissection or coarctation at the level of the thoracic aorta.


Locations(31)

University of Colorado Anschutz

Aurora, Colorado, United States

University of South Florida - Tampa General

Tampa, Florida, United States

Indiana University Health

Indianapolis, Indiana, United States

Duke University

Durham, North Carolina, United States

East Carolina University

Greenville, North Carolina, United States

University Hospitals Cleveland Medical Center

Cleveland, Ohio, United States

Ohio State University

Columbus, Ohio, United States

Lehigh Valley Hospital

Allentown, Pennsylvania, United States

University of Pennsylvania

Philadelphia, Pennsylvania, United States

Virginia Commonwealth University

Richmond, Virginia, United States

UZ Gent

Ghent, Belgium

AZ Groeninge Kortrijk

Kortrijk, Belgium

UZ Leuven

Leuven, Belgium

Hamilton General

Hamilton, Ontario, Canada

CHU Bordeaux

Bordeaux, France

CHU Clermont Ferrand

Clermont-Ferrand, France

CHU de Dijon

Dijon, France

CHU de Lille

Lille, France

Hôpital Nord Marseille

Marseille, France

CHU de Rennes

Rennes, France

Hôpitaux Universitaires de Strasbourg - Hôpital Civil

Strasbourg, France

CHU de Toulouse - Hôpital Rangueil

Toulouse, France

Charité Berlin

Berlin, Germany

Uniklinik Bonn

Bonn, Germany

UNIVERSITÄTSKLINIKUM FREIBURG/Bad Krozingen

Freiburg im Breisgau, Germany

UKE Hamburg

Hamburg, Germany

Heart Center Leipzig

Leipzig, Germany

Universitätsmedizin Mainz (University Hospital Mainz)

Mainz, Germany

Ludwig-Maximilian Universität (LMU) Klinikum

Munich, Germany

Semmelweis University Heart and Vascular Center

Budapest, Budapest, Hungary

Amphia Hospital (Ziekenhuis) Breda

Breda, Netherlands

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NCT04545502


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