HMB and Exercise-induced Muscle Damage
The Effect of β-hydroxy-β-methylbutyrate Supplementation on Muscle Damage Induced by Resistance Exercise
Poznan University of Physical Education
30 participants
Nov 1, 2019
INTERVENTIONAL
Conditions
Summary
The study aims at assessing the influence of β-hydroxy-β-methylbutyrate (HMB) supplementation (4.0 g/day) supplemented for 7 days in a group of speed-strength trained individuals on lower-body strength performance, selected muscle histological, molecular and blood markers of muscle recovery in response to resistance exercise-induced muscle damage.
Eligibility
Inclusion Criteria6
- written informed consent from all participants before the study
- a current medical clearance to practice sports,
- training experience: at least 1 year strength training programs that include lower limbs,
- minimum of 3 workout sessions (strength/resistance training) a week,
- protein intake in customary diet and during the study protocol \> 1.6g / kg of body mass per day,
- individual maximum strength greater than 2.5 times the body weight for the 1RM test in the leg-press.
Exclusion Criteria9
- current injury,
- any health-related contraindication,
- declared general feeling of being unwell,
- unwilling to follow the study protocol,
- serious disease or metabolic problems,
- intake of creatine, caffeine or beta-alanine, or other ergogenic supplements 3 months before the beginning of the study,
- history of anabolic androgenic steroids or drugs use that may interfere with muscle mass control (eg, corticosteroids), or affect physical performance,
- smoking and tobacco use,
- presence of infectious disease in the previous 4 weeks of the study.
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Interventions
Group taking oral HMB supplementation in a blinded capsule form.
Group taking oral supplementation with placebo (corn starch) in a blinded capsule form.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT04549610