RecruitingNot ApplicableNCT04556045

Exercise Therapy and Radiation Therapy (EXERT) for Metastatic Prostate Cancer


Sponsor

Case Comprehensive Cancer Center

Enrollment

80 participants

Start Date

Dec 11, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

This study is being done to determine if patients receiving personalized exercise therapy (versus those who do not receive personalized exercise therapy) have improved quality of life and physical functioning after completing their radiation therapy. Second, the study is being done to find if the quality of life changes during therapy correlate with measurements of inflammation in the blood. Third, the study is being done to see if adding exercise therapy to radiation therapy will improve survival.


Eligibility

Sex: MALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study tests whether adding a structured exercise program alongside stereotactic body radiation therapy (a precise form of radiation delivered in 5 sessions) can improve outcomes for men with metastatic prostate cancer. **You may be eligible if...** - You are a male 18 or older with prostate cancer that has spread to lymph nodes or other parts of the body - You are receiving or planned to receive stereotactic body radiation therapy (5 fractions) - You speak and read English fluently - You are physically able to perform some level of exercise - Your radiation oncologist approves your participation **You may NOT be eligible if...** - You already exercise more than 90 minutes per week - You have a medical reason that prevents you from exercising - You have significant heart problems (Class II-IV heart failure, recent heart attack or stenting within 6 months, uncontrolled irregular heartbeat) - You have other serious conditions like blood clots, pulmonary embolism, or respiratory failure Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALExercise therapy

The exercise therapy intervention will last 4 weeks. Each participant assigned to this intervention will receive a personalized ET regimen, including in-person, supervised exercise sessions; other activities to be followed at home. Participants will exercise between one and seven times per week depending on their tolerance to the treatment and exercise program.


Locations(1)

University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center

Cleveland, Ohio, United States

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NCT04556045


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