Safety and Device Performance of the Uriprene® Degradable Temporary Ureteral Stent Following Uncomplicated Ureteroscopy

This study tests the Uriprene — a novel biodegradable (self-dissolving) ureteral stent — in patients who have just had uncomplicated ureteroscopy for kidney or ureteral stones. Standard ureteral stents are placed after stone removal to keep the ureter open while it heals, but these must be removed in a separate procedure. The Uriprene stent is designed to dissolve on its own, potentially eliminating the need for a removal procedure and reducing patient discomfort and healthcare burden. The study is for adults aged 21 to 80 who have just completed a successful, uncomplicated ureteroscopy on one side for a kidney or ureteral stone. Participants must be willing and able to attend all follow-up visits. You may be eligible if: - You are between 21 and 80 years old - You have just had a successful, uncomplicated ureteroscopy for a kidney or ureteral stone - You are otherwise healthy enough to participate and can attend all follow-up visits You may NOT be eligible if: - You have a known abnormality of the urinary tract, ureteral stricture, or blockage - You have a urothelial (bladder/ureteral) cancer or renal tumor - You have an active urinary tract infection - Your kidney function is significantly impaired (creatinine above 2.5 mg/dL) - You are pregnant or breastfeeding - You have a solitary kidney - You have a bleeding disorder or are on blood thinners (other than antiplatelet agents) Talk to your doctor to see if this trial is right for you.