RecruitingNCT04567446

Discovery of Microbiome-based Biomarkers for Patients With Cancer Using Metagenomic Approach

Discovery of Microbiome-based Biomarkers for Patients With Cancer Using Metagenomic


Sponsor

Gustave Roussy, Cancer Campus, Grand Paris

Enrollment

1,100 participants

Start Date

Jan 22, 2018

Study Type

OBSERVATIONAL

Conditions

Summary

Multicentric prospective study with collection of biological samples as part of type II research


Eligibility

Inclusion Criteria3

  • Patient with cancer who will start treatment anticancer (see cohorts).
  • Patient information and signature of the consent form before any specific procedure for the study. The patient must be able and must be inclined to cooperate in the study procedures.
  • Patient affiliated to a social security scheme or beneficiary of a similar scheme.

Exclusion Criteria2

  • Pregnant or lactating woman
  • Patient under guardianship or curatorship or deprived of liberty by a decision judicial or administrative or patient unable to give his consent.

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Interventions

OTHERStool

collection at baseline (or before the third injection), at the first evaluation (CT-scan), at ≥ 6 months after the first injection, at toxicity and at relapse, at 1 week after the end of antibiotics treatment

OTHERBlood sample

20 mL collection at baseline (or before the third injection), at the first evaluation (CT-scan), at ≥ 6 months after the first injection, at toxicity and at relapse, at 1 week after the end of antibiotics treatment


Locations(9)

Gustave Roussy

Villejuif, Val De Marne, France

Centre hospitalier du Pays d'Aix

Aix-en-Provence, France

Centre Pierre Curie

Beuvry, France

Clinique du Flandre

Coudekerque-Branche, France

CHRU Lille - Hôpital Calmette

Lille, France

Centre Léon Bérard

Lyon, France

Hôpital St Louis

Paris, France

Hôpital Foch

Suresnes, France

Centre hospitalier TOULON - Sainte-Musse

Toulon, France

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