Effect of the MobiusHD® in Patients With Heart Failure

This study is testing a small implantable device called MobiusHD, which is placed in the carotid artery in your neck. It works by activating natural pressure sensors (baroreceptors) to help lower blood pressure and reduce strain on the heart in people with heart failure. **You may be eligible if...** - You are 18 or older - You have heart failure with reduced pumping function (ejection fraction of 40% or less) - You are classified as NYHA Class II, III, or ambulatory Class IV heart failure (symptoms with mild to moderate activity) - Your heart failure has been stable on standard medications for at least 4 weeks - You can walk a moderate distance in 6 minutes (between 150 and 400 meters) **You may NOT be eligible if...** - You have had a prior stroke with permanent disability, brain bleeding, or serious brain injury - Your kidneys are significantly impaired - You have severe blockages in your carotid arteries - Your BMI is over 45 - You have had a cardiac resynchronization device placed in the last 6 months Talk to your doctor to see if this trial is right for you.