Diagnostic and Prognostic Value of Cardiac Biomarkers for Early Coronary Bypass Occlusion in Patients Undergoing Coronary Revascularization
University Hospital, Basel, Switzerland
480 participants
Jul 1, 2021
OBSERVATIONAL
Conditions
Summary
This study is to evaluate the correlation between hs-cTn level as cardiac biomarker for ischemia and early graft occlusion as assessed by CCT in patients undergoing coronary bypass surgery.
Eligibility
Inclusion Criteria1
- patients with isolated coronary bypass surgery
Exclusion Criteria8
- Patients withholding or lacking informed consent
- Patients requiring a concomitant procedure
- Patients with known allergy to iodine-containing contrast agents
- Renal function impairment (serum creatinine \>140 mmol/l; estimated glomerular filtration rate (GFR) \<30 ml/min/1.73 m2).
- Pregnancy
- Unstable clinical state or severe heart failure
- Patients with registered MI and registered bypass occlusion in coronary angiogram
- Patients that didn't undergo a CCT prior to discharge
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Interventions
The clinical data from the patients enrolled in the study, such as the medical history, functional state, and EuroSCORE, and the hematological, basic renal, hepatic, and metabolic chemistry findings (including cTn as defined per the protocol), the operative data (operating time, blood loss, cardiopulmonary and cross-clamp time, number of arterial and venous grafts, the number of distal anastomoses, flow measured at all bypass grafts at the end of the intervention and the need for an assist device) and CCT scan data (at discharge from hospital facility) will be obtained from the hospital records. The data will be entered into a database.
Locations(3)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT04595630