Lung Function, Exercise Capacity, and Serology Responses in Patients With COVID-19
Chinese University of Hong Kong
700 participants
May 22, 2020
OBSERVATIONAL
Conditions
Summary
(a) Objectives 1. To assess the full lung function, exercise capacity, quality of life in patients with COVID-19 over 2 years. 2. To assess the longevity of the serology response to SARS-CoV2. 3. To investigate the association of the neutralization titer in plasma from different vaccinated cohorts to its protection of infection using in vivo model 4. To investigate the SARS-CoV-2 specific cellular and humoral immunities as well as their determinant factors from community subjects who have received different types of COVID-19 vaccines. 5. To assess the third booster dose for subjects who have poor antibody response despite having received two doses of CoronaVac (Sinovac)
Eligibility
Exclusion Criteria1
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Interventions
Healthy individuals with low antibody levels after 2 doses of CoronaVac vaccine to receive one additional dose of CoronaVac vaccine
Healthy individuals with low antibody levels after 2 doses of CoronaVac vaccine to receive one additional dose of BionTech vaccine
Healthy individuals to receive Coronavac vaccine 2 doses, 21 days apart
Healthy individuals to receive BionTech vaccine 2 doses, 21 days apart
Locations(1)
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NCT04611243