RecruitingNot ApplicableNCT04629326

PD-L1 Targeting Molecular Imaging of Solid Tumors


Sponsor

Peking University Cancer Hospital & Institute

Enrollment

20 participants

Start Date

Jul 20, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

The objective of the study is to constrcut a noninvasive approach WL12 PET/CT to detect the PD-L1 expression of tumor lesions in patients with gastrointestinal tumors and to identify patients benefiting from anti-PD-1/L1 treatment.


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • \. Aged \>18 years old; ECOG 0 or 1;
  • \. Patients with Gastrointestinal tumors;
  • \. Has at least one measurable target lesion according to Response Evaluation Criteria in Solid Tumors (RECIST V1.1);
  • \. life expectancy \>=12 weeks.

Exclusion Criteria6

  • \. Significant hepatic or renal dysfunction;
  • \. Is pregnant or ready to pregnant;
  • \. Cannot keep their states for half an hour;
  • \. Refusal to join the clinical study;
  • \. Suffering from claustrophobia or other mental diseases;
  • \. Any other situation that researchers think it is not suitable to participate in the experiment.

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Interventions

OTHER68Ga-WL12 PET/CT

WL12, labeled with PET radio-nuclide ( Ga-68 )will be used as a molecular imaging tracer for PET/CT scanning


Locations(1)

Beijing Cancer Hospital

Beijing, Beijing Municipality, China

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NCT04629326


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