Low or High Botox Dilution for the Hemiplegic Gait?

This study is comparing two different dilutions of Botox (botulinum toxin) injections to see which works better for treating a walking problem called hemiplegic gait with equinovarus deformity. Hemiplegia refers to weakness or paralysis on one side of the body, often caused by a stroke or brain injury. Equinovarus deformity means the foot turns inward and downward, making it difficult to walk normally. Botox injections relax overactive muscles and are commonly used to improve this condition. The researchers want to find out whether a high-dilution or low-dilution Botox injection leads to better walking outcomes. This is important because the way Botox spreads in muscle tissue depends on how it is diluted, and different dilutions may produce different effects on gait. You may be eligible if: - You have equinovarus foot deformity - You score an average of 3 on the Ashworth spasticity scale (indicating moderate muscle stiffness) - You are able to walk indoors, either freely or with a cane - You are 18 years of age or older You may NOT be eligible if: - You have a mental illness that affects your walking pattern - You have a musculoskeletal disease that significantly interferes with your gait Talk to your doctor to see if this trial is right for you.