RecruitingNot ApplicableNCT04637438
Fecal Microbiota Transplantation in Postoperative Crohn's Disease
Sponsor
Tampere University Hospital
Enrollment
20 participants
Start Date
May 18, 2021
Study Type
INTERVENTIONAL
Conditions
Summary
This pilot study aims to detect possible trends or signals suggesting efficacy of FMT on prevention of delay of POR, to determine the safety of FMT in post operative CD, and asses if a full randomised controlled trial is feasible in this setting. With microbiota analysis we aim to assess if changes in gut microbiota are related to disease course of CD after operation.
Eligibility
Min Age: 18 YearsMax Age: 120 Years
Inclusion Criteria3
- Over 18 years
- Able to provide written consent
- Stricturing and/or fistulizing Crohn's disease needing ileocecal or ileal resection
Exclusion Criteria5
- Pregnancy
- Active infection, abscess or fistula at the time of the first colonoscopy
- Life expectancy \<1 year
- Unable to provide written consent
- Use on antibiotics or probiotics at the time of first colonoscopy
Interventions
OTHERFecal Microbiota Transplantation
FMT via colonoscopy
OTHERPlacebo
Water infusion via colonoscopy
Locations(2)
View Full Details on ClinicalTrials.gov
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NCT04637438
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