RecruitingNot ApplicableNCT04637438

Fecal Microbiota Transplantation in Postoperative Crohn's Disease


Sponsor

Tampere University Hospital

Enrollment

20 participants

Start Date

May 18, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

This pilot study aims to detect possible trends or signals suggesting efficacy of FMT on prevention of delay of POR, to determine the safety of FMT in post operative CD, and asses if a full randomised controlled trial is feasible in this setting. With microbiota analysis we aim to assess if changes in gut microbiota are related to disease course of CD after operation.


Eligibility

Min Age: 18 YearsMax Age: 120 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether fecal microbiota transplantation (FMT) — transferring gut bacteria from a healthy donor to a patient — can help prevent Crohn's disease from coming back after surgery. FMT aims to restore a healthy balance of gut bacteria, which may reduce inflammation and prevent recurrence. **You may be eligible if...** - You are over 18 years old - You have Crohn's disease with complications (narrowing or fistulas) that require surgery to remove part of the bowel - You are able to provide written consent **You may NOT be eligible if...** - You are pregnant - You have an active infection, abscess, or fistula at the time of the first colonoscopy - Your life expectancy is less than 1 year - You are currently taking antibiotics or probiotic supplements Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

OTHERFecal Microbiota Transplantation

FMT via colonoscopy

OTHERPlacebo

Water infusion via colonoscopy


Locations(2)

Tampere University Hospital

Tampere, Finland

Tampere University Hospital

Tampere, Finland

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT04637438


Related Trials