RecruitingNot ApplicableNCT04649125

Advanced Techniques For Single-fraction Palliative Radiotherapy Versus Standard Multi Fraction Radiation


Sponsor

Royal North Shore Hospital

Enrollment

100 participants

Start Date

May 31, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

The aim of the study is to determine if single fraction dose escalated palliative radiotherapy results in a prolonged duration of benefit for patients otherwise suitable for Multifraction (5-10#) palliative radiation. The primary endpointis to determine the percentage of patients who have achieved a substantial benefit from palliative radiotherapy and have not redeveloped symptoms by 12 months post treatment


Eligibility

Inclusion Criteria3

  • Metastatic cancer
  • Recommended for 5-10 fractions palliative radiation
  • Patients with spinal cord compression are eligible for enrolment

Exclusion Criteria2

  • Unwilling or unable to give informed consent
  • Patients who are recommended for single fraction palliative radiation

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Interventions

RADIATIONdose escalation

single fraction dose escalation to the tumour


Locations(1)

Royal North Shore Hospital

Saint Leonards, New South Wales, Australia

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NCT04649125


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