RecruitingNot ApplicableNCT04651010

Predictive Multimodal MRI Factors in Subacute Cerebral Artery Occlusiontreated by Thrombectomy (PIMISUTT)

Predictive Multimodal MRI Factors in Subacute Cerebral Artery Occlusiontreated by Thrombectomy (PIMISUTT


Sponsor

Poitiers University Hospital

Enrollment

50 participants

Start Date

Nov 15, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

Our study aims to measure metabolic and functional parameters of the infarcted territory by multimodal cerebral MRI in patients diagnosed with unilateral proximal occlusion of the middle cerebral artery and treated by thrombectomy in order to correlate those parameters to clinical outcome (evaluated by modified Rankin score) at 3 months. We aim to find early radiologic predictive factors for favorable clinical outcome in this population of patients.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study examines whether MRI brain scans taken before a procedure called thrombectomy (a catheter-based procedure to remove a blood clot from a brain artery) can predict how well a patient will recover afterward. The study focuses on patients with a stroke caused by a middle cerebral artery blockage, and aims to identify imaging markers that predict which patients benefit most from thrombectomy, and which may face greater risks. Participants will have specialized MRI scans taken before and after thrombectomy, and their recovery will be tracked over time. This could help doctors make better treatment decisions in future stroke cases. **You may be eligible if you:** - Are 18 years of age or older - Are hospitalized at Poitiers University Hospital - Have been diagnosed with an acute middle cerebral artery occlusion (stroke) by CT scan or MRI - Have a stroke severity score (NIHSS) of 6 or above at admission - Are scheduled to receive thrombectomy (with or without clot-dissolving medication) **You may NOT be eligible if you:** - Cannot be properly informed about the study (you or your relatives) - Have existing cognitive impairment that makes MRI interpretation difficult - Cannot undergo MRI due to contraindications (e.g., pacemaker, metal implants) - Are too unstable to tolerate an hour-long examination **Talk to your doctor** if you or a family member is being treated for a stroke and you want to understand what research is available to improve outcomes.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERMultimodal MRI

Multimodal MRI will be realized between 12 and 24 hours after thrombectomy


Locations(1)

CHU Poitiers

Poitiers, France

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NCT04651010