RecruitingNCT04664569

National Bacterial Meningitis Study

National Observatory of Bacterial Meningitis in Children and Newborns


Sponsor

Association Clinique Thérapeutique Infantile du val de Marne

Enrollment

8,230 participants

Start Date

Jan 1, 2001

Study Type

OBSERVATIONAL

Conditions

Summary

Bacterial meningitis is a major cause of morbidity and mortality in childhood. Antibiotic treatment recommendations are based on epidemiological and susceptibility data. The epidemiology of bacterialméningitis has changed in recent years, mainly owing to widespread use of different conjugate vaccines. The aim of this prospective national survey is to describe epidemiology of bacteria implicated in bacterial meningitis in children.


Eligibility

Min Age: 0 YearsMax Age: 18 Years

Inclusion Criteria2

  • clinical signs of meningitis, associated with positive cerebrospinal fluid (CSF) culture and/or positive CSF antigen testing (Escherichia coli K1, N. meningitidis serogroups B, A, C, Y and W-135, group B streptococci, Hib, or S. pneumoniae), and/or positive CSF polymerase chain reaction (PCR), and/or positive blood culture with CSF pleocytosis (\> 10 cells/µL).
  • purpura fulminans

Exclusion Criteria1

  • \-

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Interventions

OTHERobservational study

observational study


Locations(1)

ACTIV

Créteil, France

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NCT04664569


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