RecruitingNCT04794595

Clinical Features and Outcomes of CBP Versus Non-CBP in Septic Children

Clinical Features and Outcomes of Continuous Blood Purification Versus Non-continuous Blood Purification in Pediatric Patients With Sepsis or Septic Shock


Sponsor

Children's Hospital of Fudan University

Enrollment

90 participants

Start Date

Dec 1, 2020

Study Type

OBSERVATIONAL

Conditions

Summary

The effect of continuous blood purification (CBP) in children is unclear. Also, the timing of early application is still being explored. In this study, we need to explore the efficacy and the timing of application of CBP in children with sepsis or septic shock.


Eligibility

Min Age: 28 DaysMax Age: 18 Years

Inclusion Criteria2

  • Age of 29d to 18 years old;
  • Children diagnosed with sepsis requiring blood purification.

Exclusion Criteria2

  • with a history of a duration of PICU stay \<24 h
  • active bleeding, including cerebral hemorrhage

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Interventions

PROCEDURECBP

continuous blood purification can prevent or treat fluid overload in children with septic shock or other sepsis-associated organ dysfunction who are unresponsive to fluid restriction and diuretic therapy management of septic AKI patients, particularly those with hemodynamic instability or fluid overload. Also, it can remove cytokines


Locations(1)

Children'S Hospital of Fudan University

Shanghai, Shanghai Municipality, China

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NCT04794595


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