RecruitingNCT04665674

Adult Pulmonary Langerhans Cell Histiocytosis: a National Registry-based Prospective Cohort Study

Enquête épidémiologique Sur la prévalence et le Pronostic de l'Histiocytose Langerhansienne Pulmonaire de l'Adulte en France


Sponsor

Assistance Publique - Hôpitaux de Paris

Enrollment

500 participants

Start Date

Jan 1, 2004

Study Type

OBSERVATIONAL

Conditions

Summary

The long-term outcomes of adult patients with pulmonary Langerhans cell histiocytosis (PLCH), particularly survival, is largely unknown. This is the first prospective study in the field evaluating the long-term outcomes of PLCH patients. This french countrywide registry-based study included a large cohort of PLCH patients followed for a sufficiently long period to address risk factors of long-term outcomes of PLCH patients.


Eligibility

Min Age: 18 Years

Inclusion Criteria2

  • Age >= 18 years
  • Diagnosis of PLCH was either histologically confirmed on a biopsy of an involved tissue, or based on the combination of the following criteria: 1) an appropriate clinical picture; 2) a typical nodulo-cystic pattern on lung high-resolution computed tomography (HRCT) and 3) exclusion of alternative diagnoses

Exclusion Criteria1

  • \-

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Interventions

OTHERStandard of care

Standard of car of pulmonary Langerhans cell histiocytosis (PLCH)


Locations(1)

French national reference centre for Histiocytoses

Paris, France

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NCT04665674


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