RecruitingNCT04666727

Role of Diet on the Microbiome of the Digestive System

The Role of Diet and the Microbiome in Inducing Somatic Mutations in Colorectal Epithelial Cells and Its Predisposition to Carcinogenesis - A Pilot Study

Sponsor

M.D. Anderson Cancer Center

Enrollment

30 participants

Start Date

Sep 29, 2020

Study Type

OBSERVATIONAL

Conditions

Colorectal Carcinoma

Summary

This study is to learn more about how diet affects the microbiome (bacteria and microorganisms) of the digestive system. Researchers want to learn if this, in turn, has an effect on if and how people then develop colorectal cancer.

Eligibility

Min Age: 45 Years

Plain Language Summary

Simplified for easier understanding

This study is investigating how diet affects the bacteria living in your digestive system (your gut microbiome), and what that means for your colon health. Researchers are comparing the gut bacteria of strict vegetarians against omnivores (people who eat both plant and animal foods) during routine colonoscopy screenings. **You may be eligible if you:** - Are 45 years of age or older - Are scheduled for a screening colonoscopy - Follow a strict vegetarian diet OR an omnivorous (mixed food) diet - Are a non-smoker - Are willing to provide stool, colon tissue, and blood samples, and complete an online diet questionnaire **You may NOT be eligible if you:** - Currently smoke - Do not fall into either a strictly vegetarian or omnivorous diet category - Are unwilling or unable to complete the required samples and questionnaire Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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