Safety and Efficacy of the Sentinel Cerebral Protection Device in Atrial Fibrillation Ablation

This study is testing a small device called the Sentinel, which is placed in the bloodstream during atrial fibrillation (AF) ablation procedures to catch any debris that might travel to the brain and cause a stroke. The aim is to see if this protection device reduces the risk of silent brain injury during the procedure. **You may be eligible if...** - You are 18 or older - You have atrial fibrillation (an irregular heartbeat) and are scheduled for a catheter ablation procedure (radiofrequency, pulsed field, or cryo-balloon) - You are having the procedure because medications have not worked or you cannot tolerate them - You are able to give informed consent **You may NOT be eligible if...** - Your anatomy (blood vessel size or shape) is not compatible with the Sentinel device - You have other conditions that make participation unsafe Talk to your doctor to see if this trial is right for you.