RecruitingNot ApplicableNCT04686097
Percutaneous Electrocoagulation Versus Sclerosing Foam for Patients With Incompetent Perforating Veins
Percutaneous Electrocoagulation Versus Sclerosing Foam for Patients With Incompetent Perforating Veins : A Multi-center Prospective Randomized Controlled Trial
Sponsor
Second Affiliated Hospital, School of Medicine, Zhejiang University
Enrollment
84 participants
Start Date
Jan 1, 2021
Study Type
INTERVENTIONAL
Conditions
Summary
This study aimed to compare the efficacy of punctured electrocoagulation and sclerotherapy in the treatment of incompetent perforator veins.
Eligibility
Min Age: 18 YearsMax Age: 80 Years
Inclusion Criteria1
- (1) outward flow of less than 500 ms duration, with a diameter of >3.5 mm; (2) According to the CEAP classification method specified by the International Venous Federation, patients with C4b~C6 grades are included.
Exclusion Criteria1
- (1)age < 18 years or age > 80 years; (2)with malignant tumors and life expectancy < 1 year; (3)with past or current history of deep vein thrombosis and/or pulmonary embolism in the lower extremities; (4)with congenital venous malformations (K-T syndrome, arteriovenous fistula and etc.; (5)inability to walk, long-term braking, restrictive bed rest; severe ischemia of lower extremities or diagnosed severity of peripheral artery occlusive disease; (6)according to the researcher's judgment, it is not suitable for foam hardener and puncture coagulation treatment; (7)allergic to the drugs and equipment materials involved in the research; (8)with inferior vena cava and/or iliac vein stenosis or occlusion; (9)with autoimmune disease, receiving chemotherapy, hormone therapy or immunomodulatory treatment; (10)other underlying severe diseases; women who are pregnant, breastfeeding or have pregnancy plans during the study period; (11)the patient cannot cooperate to complete the inspection and follow-up required by the study.
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Interventions
PROCEDUREtreatment: puncture of coagulation
ultrasound-guided puncture of coagulation
PROCEDUREtreatment: sclerosing agent injected
ultrasound-guided sclerosing agent injected
Locations(5)
View Full Details on ClinicalTrials.gov
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NCT04686097