RecruitingNCT04686253

Internal Microstructure of Patent Foramen Ovale Related to Stroke

Internal Microstructure of Patent Foramen Ovale Related to Cryptogenic Stroke, Transient Ischemic Attack or Migraine

Sponsor

China National Center for Cardiovascular Diseases

Enrollment

1,200 participants

Start Date

Dec 23, 2020

Study Type

OBSERVATIONAL

Conditions

Patent foramen ovale

Summary

This study aims to (1) investigate the internal microstructure of patent foramen ovale related to cryptogenic stroke, transient ischemic attack or migraine and determine the effectiveness of transcatheter closure in these patients; (2) evaluate the microstructural features of asymptomatic patients with PFO and make a follow-up；(3) perform an untargeted metabolomics analysis using plasma samples from right atrium and left atrium and shunt provocative test was conducted;(4) collect the blood sample from PFO tunnel;(5) cardiac CTA was performed to evaluate the position and morphology of device.

Eligibility

Min Age: 16 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying not appliable for people with patent foramen ovale. The study is currently recruiting participants at 2 locations. People eligible for this study include aged 16 Years to 65 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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