RecruitingNCT04716257

A Prospective, Multi-center, Real-world Study of Ovarian Metastatic Colorectal Cancer Patients

Impact of Different Treatment Strategies on the Prognosis of Ovarian Metastatic Colorectal Cancer Patients: a Prospective, Multi-center, Real-world Study

Sponsor

West China Hospital

Enrollment

400 participants

Start Date

Jan 14, 2021

Study Type

OBSERVATIONAL

Conditions

Colorectal, Cancer Ovarian Metastasis

Summary

This prospective, multi-center, real-world study is conducted to investigate the impact of different treatment strategies (systemic chemotherapy combined with oophorectomy or with other local treatment or chemotherapy alone) on the prognosis of ovarian metastatic colorectal cancer patients.

Eligibility

Sex: FEMALEMin Age: 18 Years

Inclusion Criteria7

Histologically confirmed colorectal adenocarcinoma;
Histologically or radiologically diagnosed with ovarian metastasis, whether or not combined with metastases in other organs;
Women ≥18 years of age;
Eastern Cooperative Oncology Group performance status score ≤2;
Available imaging data if the disease is measurable according to RECIST criteria version 1.1; patients are eligible if there is no measurable lesion.
Complete medical records;
Informed consent form signed.

Exclusion Criteria4

Not ovarian metastatic colorectal cancer confirmed by radiology or histology;
Drug abuse or other medical, psychological and social disorders that would interfere with cooperation with the requirements of the study;
Other conditions that would influence patient compliance;
Pregnant or breastfeeding female; male and female unwilling to take any contraceptive measures.