RecruitingPhase 4NCT04729686

The Pericapsular Nerve Block in Total Hip Arthroplasty

The Pericapsular Nerve Block in Total Hip Arthroplasty: A Randomized, Controlled Trial

Sponsor

LifeBridge Health

Enrollment

78 participants

Start Date

Dec 9, 2020

Study Type

INTERVENTIONAL

Conditions

hip osteoarthritis Hip Arthropathy

Summary

In order to continue progressing towards outpatient total hip arthroplasty (THA), methods to adequately manage postoperative pain is of paramount importance. The purpose of this study is to quantify the effectiveness of the pericapsular nerve block in total hip arthroplasty in comparison to the fascia iliaca nerve block.

Eligibility

Min Age: 18 YearsMax Age: 80 Years

Inclusion Criteria6

Provision of signed and dated informed consent form
Stated willingness to comply with all study procedures and availability for the duration of the study
Planned primary total hip arthroplasty with anterior (Smith-Peterson) approach
ASA score of 1 to 3
Indicated for one of the two nerve block groups
Must be opioid naïve at screening as defined by the FDA - According to the Food and Drug Administration, opioid-tolerant patients were those currently receiving or who had previously received 60 mg PO morphine per day, 25 mcg transdermal fentanyl per hour, 30 mg PO oxycodone per day, 8 mg PO hydromorphone per day, 25 mg PO oxymorphone per day, 60 mg PO hydrocodone per day, or an equivalent dose of another opioid for a duration of one week or longer (16)

Exclusion Criteria7

Current or previous diagnosis of "chronic pain"
Opioid tolerant at time of screening (for a week or longer, at least 60 mg of morphine daily, or at least 30 mg of oral oxycodone daily, or at least 8 mg of oral hydromorphone daily or an equianalgesic dose of another opioid.)
Diagnosis of ankylosing spondylitis
Allergy to any potential medications utilized in any of the two groups
Conversion of patient to general anesthesia intraoperatively
Treatment with another investigational drug or other intervention for pain
Any condition(s) or diagnosis, both physical or psychological, or physical exam finding in the opinion of the investigator that would precludes participation