RecruitingNCT04733729

Covid-19 in Hematological Malignancies

Epidemiology of COVID-19 Infection in Patients With Hematological Malignancies: A European Haematology Association Survey


Sponsor

Sorveglianza Epidemiologica Infezioni Fungine Emopatie Maligne

Enrollment

3,000 participants

Start Date

Mar 1, 2020

Study Type

OBSERVATIONAL

Conditions

Summary

The overall purpose of this project is to better understand the epidemiology of COVID-19 in patients with hematological malignancies (including hematopoietic stem cell transplant recipients) in the different European Countries. The results obtained will allow us to better know the prevalence of this complication in the different categories of patients with hematological malignancies (HMs). In order to attain the objectives previously described we will develop a multicentre, international, observational, retrospective and prospective study of consecutive cases of COVID-19 among HMs. There will be a clinical follow-up of the patients included in this study to observe the survival rate. Data collected form this study will be evaluated with a descriptive analysis.


Eligibility

Min Age: 18 YearsMax Age: 99 Years

Inclusion Criteria5

  • Age equal to or greater than 18 years of age.
  • History of hematological malignancies (acute leukemias, myelodysplastic syndromes, myeloproliferative neoplasms, lymphomas, myeloma, chronic myeloprolipherative disorders) at any stage/status.
  • Active hematological malignancies at any stage/status.
  • Diagnosis of hematological malignancy (acute leukemias, myelodysplastic syndromes, myeloproliferative neoplasms, lymphomas, myeloma, chronic myeloprolipherative disorders) at any stage/status.
  • SARS-CoV-2 positive test (nasopharyngeal, BAL, fecal), documented by Real-Time Reverse Transcriptase (RT)-PCR Diagnostic Panels.

Exclusion Criteria3

  • Hematological diseases, other than hematological malignancies.
  • Not tested positive for SARS-CoV-2
  • Patients "off therapy" for more than 5 years

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Locations(6)

ASST-Spedali Civili

Brescia, Italy

AOU Policlinico Federico II

Naples, Italy

Fondazione Policlinico A. Gemelli IRCCS

Rome, Italy

Istituto Nazionale Tumori Regina Elena IFO

Rome, Italy

Osp. di Circolo-Fondazione Macchi

Varese, Italy

AOUI Verona

Verona, Italy

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NCT04733729