RecruitingNCT04755764

Effect of Labetalol, Atenolol, and Nifedipine on Maternal Hemodynamics Measured by ICG in Early Pregnancy

The Effect of Labetalol, Atenolol, and Nifedipine on Maternal Hemodynamics Measured by Impedance Cardiography in Early Pregnancy


Sponsor

Marshall University

Enrollment

60 participants

Start Date

Mar 3, 2021

Study Type

OBSERVATIONAL

Conditions

Summary

The purpose of the research is to characterize the effect of labetalol, atenolol, and nifedipine on maternal hemodynamics early in pregnancy. Patients will be given medication based on their hemodynamics and asked to return for a repeat measurement.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 45 Years

Plain Language Summary

Simplified for easier understanding

This study compares how three different blood pressure medications — labetalol, atenolol, and nifedipine — affect the heart and circulation in pregnant women with high blood pressure during the first trimester, measured using a non-invasive monitoring technique called impedance cardiography (ICG). **You may be eligible if...** - You are 18 to 45 years old - You are pregnant at less than 15 weeks gestation - You are being seen at a maternal hypertension clinic - You speak English and are willing to give consent **You may NOT be eligible if...** - You are under 18 or over 45 years old - You are more than 15 weeks pregnant - You do not speak English Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGLabetalol

Beta blocker

DRUGAtenolol

Beta blocker

DRUGNifedipine

Calcium channel blocker


Locations(1)

Maternal Hypertension Center at Cabell Huntington Hospital

Huntington, West Virginia, United States

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NCT04755764


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