RecruitingNot ApplicableNCT04757168

Changes in Regional and Global Cardiac Contractility After Stimulation in Scar Zone with the NOGA System

Sponsor

University Hospital, Toulouse

Enrollment

12 participants

Start Date

Feb 23, 2022

Study Type

INTERVENTIONAL

Conditions

Myocardial Infarction

Summary

Despite a decrease in voltage amplitude in post-infarction scar areas, greater voltage amplitudes are sometimes observed at the time of local extrasystoles mechanically induced by catheters. However, no study has investigated whether these electrical changes are associated with mechanical changes in local contractility. However, the voltage is closely correlated to the local contractile function as evidenced by the use of the NOGA system.

Eligibility

Min Age: 18 YearsMax Age: 85 Years

Inclusion Criteria5

\- Patients who should undergo ventricular tachycardia (VT) ablation after a myocardial infarction according to current recommendations, namely: patients with ischemic heart disease (ICD) and with episodes of sustained ventricular tachycardia responsible for internal electric shocks by the implantable automatic defibrillator (ICD) (grade IB recommendation)
OR
patients with an MIC and an ICD, presenting a first episode of sustained ventricular tachycardia (grade IIa, B recommendation)
Affiliated with a social protection scheme
Having signed an informed consent

Exclusion Criteria4

Contraindication or non-indication for ventricular tachycardia ablation
Women who are pregnant or of childbearing age and without contraception, breastfeeding women
Patients without ischemic heart disease
Patients under guardianship, curatorship or legal protection.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DEVICENOGA TM probe

Each subject will be his own witness since the linear local shortening (LLS) will be measured successively in all patients before, then after stimulation of the scar zone (comparison of LLS measured in sinus rhythm then during stimulation in the scar zone for each patient. Each subject being his own witness and the two recordings being made a few minutes apart, during the same procedure.