RecruitingPhase 2Phase 3NCT04765020

Cardiorespiratory Fitness in Children and Adolescents After Cancer Treatment.

Effects of a Physical Activity Program on Cardiorespiratory Fitness in Children and Adolescents FolloWing Acute CancER Treatment: a Randomized Controlled Trial


Sponsor

Universität Duisburg-Essen

Enrollment

56 participants

Start Date

Jun 21, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

The POWER-study is a two-arm exercise intervention study for pediatric patients following acute cancer treatment. This clinical trial will investigate the effects of a 12-week moderate to high-intensity exercise program on cardiorespiratory fitness in children and adolescents beginning 6 weeks after completion of acute cancer treatment.


Eligibility

Min Age: 7 YearsMax Age: 23 Years

Inclusion Criteria4

  • Children and adolescents between 7 and 23 years of age
  • Completion of acute cancer treatment and receiving follow-up care in Krefeld (Helios Hospital Krefeld)
  • weeks post cancer-treatment
  • Signed informed consent (Parents and Patient)

Exclusion Criteria4

  • <7 years of age, >23 years of age
  • Medical condition that limits participation in one of the study arms
  • Inability to follow the training-protocol
  • Inability to carry out the spiroergometry on a cycle ergometer

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Interventions

BEHAVIORALExperimental: moderate to high-intensity exercise

Four parts: 1. Initial consultation with recommendations for general physical activity, brochure with exercise recommendations 2. Once per week multi-modal group-based exercise (endurance, strength, mobility, coordination) 3. Once per week supervised multi-modal individual training session (endurance, strength, mobility, coordination). Intensity: 60-80% of max. HR 4. Activity trackers with individual movement goals that will be adjusted every two weeks


Locations(1)

Helios Klinik Krefeld

Krefeld, Germany

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NCT04765020