RecruitingNot ApplicableNCT04776473

Treatment of Intra-articular Fractures of the Mandibular Condyle

Open Versus Closed Treatment of Intra-articular Fractures of the Mandibular Condyle: a Multicentre Randomized Controlled Trial


Sponsor

Assistance Publique - Hôpitaux de Paris

Enrollment

110 participants

Start Date

May 3, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

Intra-articular fractures of the mandibular condyle ((IAFC) are usually treated by means of physical therapy with or without transient maxillo-mandibular fixation (conservative or closed treatment). However, this can lead to incomplete manducatory function recovery due to limited mandibular mobility. During the last 15 years, a growing interest has emerged for open (surgical) treatment of these fractures. Although there is more and more evidence suggesting that the open treatment may be the treatment of choice for selected cases of subcondylar fractures, the best option remains controversial for high condylar fractures. The primary objective of the trial is to compare mandibular mobility at 3 months post-treatment between open (surgical) and closed (conservative) treatment of intra-articular fracture (high fracture) of the mandibular condyle. This study is an open multicenter randomized controlled trial with 2 parallel arms. Eligible patients will be randomized 1 :1 between open and closed-treatment group.


Eligibility

Min Age: 18 YearsMax Age: 84 Years

Inclusion Criteria8

  • Adult (≥18 y-o) < 85 years
  • Displaced non-comminuted intra-articular fracture of the mandibular condyle (IAFC) as defined by a fracture line above a horizontal line tangent to the mandibular notch
  • Objectifiable induced malocclusion and/or ramus shortening ≥2 mm on CT-scan (a ramus shortening ≥2 mm on CT-scan is necessary in case of other associated mandibular or occluso-facial fractures)
  • Unilateral or bilateral fracture
  • Isolated or associated with other facial / extra-facial skeleton / dental / soft tissue lesions
  • Treatment within 14 days post trauma
  • Affiliation to a social security regime (excepted AME)
  • Written informed consent

Exclusion Criteria8

  • Contraindication to surgical treatment (for any medical or anatomical reason, like comminuted fracture for instance)
  • Major teeth loss or edentulous patient (occlusion impossible to assess)
  • History of mandibular fracture
  • History of temporo-mandibular joint (TMJ) disorder
  • Dentofacial dysmorphosis causing significant malocclusion
  • Predictable inability to comply with the follow-up
  • Unconsciousness / severe polytrauma
  • Participation in another interventional study

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Interventions

PROCEDUREOpen treatment

Open (i.e. surgical) treatment will be performed following the usual practice of the including centre adopting a pragmatic approach.

OTHERClosed treatment

Closed (i.e. conservative) treatment will be performed following the usual practice of the including centre adopting a pragmatic approach.


Locations(7)

CHU Angers

Angers, France

Hôpital Annecy Genevois

Annecy, France

APHM - Hôpital de la Conception

Marseille, France

CHU de Nantes

Nantes, France

Hôpital Pitié-Salpêtrière

Paris, France

Hôpitaux Universitaires de Strasbourg

Strasbourg, France

CHU Purpan - Hôpital Pierre-Paul Riquet

Toulouse, France

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NCT04776473