RecruitingNot ApplicableNCT04783155

Effect of Inspiratory Muscle Training on Physiological Function and Clinical Outcomes After Lung Transplant

Effect of Inspiratory Muscle Training on Physiological Function and Clinical Outcomes After Lung Transplant: A Randomized Controlled Trial


Sponsor

Mayo Clinic

Enrollment

30 participants

Start Date

May 10, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this research is to study the effect of training the inspiratory muscles (i.e. the muscle that allow you to breath-in) on exercise capacity, quality of life, and short-term clinical outcomes in patients post lung transplant.


Eligibility

Min Age: 18 Years

Inclusion Criteria1

  • \- All patients who undergo single- or double-lung transplant at Mayo Clinic Florida.

Exclusion Criteria4

  • Patients who do not survive the intra-operative period during the transplant surgery.
  • Patients undergoing retransplantation.
  • Patients undergoing multiorgan transplantation.
  • Patients who are not willing to or who are unable to give written informed consent.

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Interventions

DEVICEPOWERBreathe Plus®

Commercially available pressure-threshold device

OTHERCardiopulmonary rehabilitation post lung transplant

Pulmonary function, lung diffusing capacity for carbon monoxide, inspiratory muscle strength, and diaphragm dimensions will be assessed in each patient. Each patient will also undergo a cardiopulmonary exercise test (CPET), 6 minute walk test, and an inspiratory muscle endurance test


Locations(1)

Mayo Clinic in Florida

Jacksonville, Florida, United States

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NCT04783155


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