Chronic Widespread Pain in HIV: Novel Mechanisms and Therapeutics

This study is looking at chronic widespread pain in people living with HIV, to better understand what causes it and whether existing treatments can help. Many people with HIV experience persistent pain throughout their body, but it is not well understood. Researchers are enrolling both HIV-positive and HIV-negative participants for comparison. **You may be eligible if...** - You are between 19 and 65 years old - You have a confirmed HIV diagnosis and are currently receiving stable HIV treatment (antiretroviral therapy), OR - You are confirmed HIV-negative (for comparison group) - You are a current patient at the UAB 1917 HIV Clinic (for HIV-positive participants) **You may NOT be eligible if...** - You are under 19 or over 65 - You are HIV-positive but not currently on stable antiretroviral treatment - You have other health conditions that meet the study's exclusion criteria Talk to your doctor to see if this trial is right for you.