RecruitingNCT04791436

Oral and Olfactory Complications of Recovered COVID-19 Patients

Oral and Olfactory Complications of Recovered COVID-19 Patients: A Prospective Cohort Study


Sponsor

University of Giessen

Enrollment

402 participants

Start Date

May 1, 2021

Study Type

OBSERVATIONAL

Conditions

Summary

This cohort study aims to investigate the long-standing chemosensory disorders and oral manifestation after recovery of the COVID-19 illness. A correlation between the long-standing symptoms and the COVID-19 severity grade will be very important to understand and clarify the aetiology of these symptoms.


Eligibility

Min Age: 18 Years

Inclusion Criteria1

  • All adult COVID-19 recovery patients (exceeding the age of 18) will be included in the study. The time between illness and study recruitment shall be at least 3 months.

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Interventions

DIAGNOSTIC_TESTGustatory and olfactory function test

The gustatory and olfactory function will be tested by using the combined Burghart Screening 12 test containing smelling sticks and taste strips (Fa. MediSense, Groningen, Netherlands). Evaluation of taste and smell is performed by offering the sticks/strips and demand a forced multiple choice.

DIAGNOSTIC_TESTMolecular assessment of saliva

Saliva samples will be taken for molecular biological determination of the oral microbiome. The microbiome is determined at the Institute for Medical Microbiology by 16s-rRNA gene analysis with Next Generation Sequencing and bioinformatics.


Locations(1)

Justus-Liebig University

Giessen, Hesse, Germany

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NCT04791436


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