RecruitingNCT04794296

Recommendations for the Treatment of Children With Acute Lymphoblastic Leukemia in the GFAOP


Sponsor

French Africa Pediatric Oncology Group

Enrollment

500 participants

Start Date

Nov 15, 2021

Study Type

OBSERVATIONAL

Conditions

Summary

The LALGFA2019 Recommendations redefine the standard risk criteria and propose to introduce anthracycline induction in so-called high-risk forms (LAL line T and LAL line B with leukocytosis greater than or equal to 50 G/L or in children less than 1 year of age or more than 10 years of age) as well as Endoxan and Methotrexate in high dose consolidation.


Eligibility

Max Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is offering children with acute lymphoblastic leukemia (ALL) — the most common childhood cancer — standardized, evidence-based treatment through the GFAOP (a pediatric oncology group in French-speaking Africa). It aims to improve survival outcomes by ensuring children receive consistent, guideline-based care. **You may be eligible if...** - You are a child between 0 and 18 years old - You have a newly diagnosed ALL (first diagnosis) - You have not yet received any chemotherapy for ALL - Your leukemia is of the FAB L1 or L2 type **You may NOT be eligible if...** - You have ALL type L3 (Burkitt lymphoma/leukemia), which requires a different treatment - You have already received chemotherapy for this leukemia - You have Down syndrome (Trisomy 21) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(3)

CHU de Treichville à ABIDJAN

Abidjan, Côte d’Ivoire

CHU Donka 030 BP 554

Conakry, Guinea

Hôpital Aristide Le Dantec, Avenue Pasteur,

Dakar, Senegal

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NCT04794296


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