Sepsis Clinical Trials

216 recruiting

Sepsis Trials at a Glance

234 actively recruiting trials for sepsis are listed on ClinicalTrialsFinder across 6 cities in 60 countries. The largest study group is Not Applicable with 49 trials, with the heaviest enrollment activity in Philadelphia, Guangzhou, and Shanghai. Lead sponsors running sepsis studies include Ain Shams University, Assistance Publique - Hôpitaux de Paris, and Children's Hospital of Fudan University.

Treatments under study

About Sepsis Clinical Trials

Looking for clinical trials for Sepsis? There are currently 216 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Sepsis trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Sepsis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 234 trials

Recruiting
Not Applicable

Veno-arterial Carbon Dioxide Partial Pressure Difference (CO2gap) for Early Resuscitation of Septic Shock

Septic ShockSepsis - to Reduce Mortality in the Intensive Care Unit
University Hospital, Clermont-Ferrand750 enrolled27 locationsNCT07179276
Recruiting
Not Applicable

Stop Sepsis Through Home Monitoring Cooperative

SepsisInfectionHome Monitoring Follow-up+1 more
University Hospital, Antwerp120 enrolled1 locationNCT06920979
Recruiting
Not Applicable

Efficacy and Safety of Cytokine Adsorption and Plasma Exchange in Patients With ACLF and Sepsis

SepsisAcute-On-Chronic Liver Failure
Third Affiliated Hospital, Sun Yat-Sen University192 enrolled1 locationNCT06562803
Recruiting
Phase 4

Aminoglycosides in Early Sepsis

Sepsis
University Hospital, Akershus1,900 enrolled5 locationsNCT06712641
Recruiting

Bispectral Index (BIS) for Classification of Procalcitonin (PCT) Sepsis Grades in Critically Ill Patients With Sepsis

Sepsis, Severe
Suez Canal University20 enrolled1 locationNCT03244293
Recruiting

NeoDoppler: New Ultrasound Technology for Continuous Monitoring of Cerebral Circulation Pilot

SepsisStrokePulmonary Hypertension+4 more
St. Olavs Hospital180 enrolled1 locationNCT06646250
Recruiting

Organ Dysfunction Score for Obstetric Patients

SepsisPregnancyPostpartum+2 more
Daniela Vasquez130 enrolled18 locationsNCT07068022
Recruiting
Phase 4

Effect of Heart Rate Control With Ivabradine on Hemodynamic in Patients With Sepsis

SepsisHemodynamicsIvabradine+1 more
Second Affiliated Hospital of Guangzhou Medical University172 enrolled3 locationsNCT05882708
Recruiting
Phase 1

A Study to Learn About How Safe BAY 3389934 is, Its Suitable Dose, and How it Affects the Participants With Sepsis Induced Coagulopathy

Sepsis
Bayer36 enrolled20 locationsNCT06854640
Recruiting
Not Applicable

Early Norepinephrine Administration and Rapid Dose Adjustment

SepsisSeptic Shock
Siriraj Hospital600 enrolled6 locationsNCT07343206
Recruiting
Phase 4

Improving Therapeutic Drug Monitoring and Dosing for Vancomycin in Young Infants With Infections (VANCAPP) (Part 2)

SepsisInfectionsBacteremia
Murdoch Childrens Research Institute40 enrolled4 locationsNCT05770622
Recruiting

Biomarkers in Infection

SepsisInflammationInfection
Beth Israel Deaconess Medical Center4,200 enrolled2 locationsNCT02545478
Recruiting

ACOD1 as a Prognostic Marker for Sepsis

Sepsis
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology52 enrolled2 locationsNCT07533994
Recruiting

Effect of oXiris Hemofilter Use in Septic Shock: A Multicenter Retrospective Cohort Study

SepsisSeptic ShockMultiorgan Failure
Seoul National University Bundang Hospital360 enrolled1 locationNCT07539883
Recruiting

Infraclavicular Axillary Vein Collapsibility Index as a Predictor of Fluid Responsiveness

Sepsis
Ain Shams University40 enrolled1 locationNCT07507877
Recruiting
Not Applicable

Peripheral Perfusion Index-guided Fluid Resuscitation for Preventing Acute Skin Failure in Elderly Critically Ill Patients

SepsisSeptic ShockAcute Skin Failure
Ying Wang216 enrolled1 locationNCT07367113
Recruiting

Febrile Infants Swedish Study

Serious Bacterial InfectionSepsisBacteremia+4 more
Region Skane2,000 enrolled11 locationsNCT07134751
Recruiting
Phase 1

A Study to Assess the Safety and Effects of Different Doses of an Investigational Drug, BAY 3389934, in Healthy Japanese Volunteers.

Sepsis Associated Disseminated Intravascular Coagulation (DIC)
Bayer16 enrolled2 locationsNCT07176728
Recruiting
Phase 2

The Treatment of Sepsis Induced Myocardial Dysfunction With Yiqilishui Formula

Sepsis Induced Myocardial Dysfunction
Dongzhimen Hospital, Beijing80 enrolled1 locationNCT06686355
Recruiting

QUELIMMUNE (SCD-PED) PediAtric SurVeillance REgistry

Acute Kidney InjuryAcute Kidney Injury Due to Sepsis
SeaStar Medical300 enrolled15 locationsNCT06517810