A New Study Evaluating the Activity of Modular CAR T for mYeloma
An Open Label, Phase 1 Study Evaluating the Activity of Modular CAR T for mYeloma
University College, London
27 participants
Apr 22, 2022
INTERVENTIONAL
Conditions
Summary
This is a Phase 1 rolling 6 trial design evaluating safety of a novel BCMA Chimeric Antigen Receptor (CAR) alone and of CAR T cells engineered to co-express BCMA CAR and a CD19 CAR in patients with relapsed / refractory Multiple Myeloma. The study will assess the feasibility of generating these Advanced Therapy Investigational Products (ATIMPs) and the safety of administering the CAR T cells (either BCMA alone or co-expressed with CD19) in patients with relapsed / refractory multiple myeloma.
Eligibility
Plain Language Summary
Simplified for easier understanding
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
Infusion with ATIMP: BCMA CAR T-cells
Infusion with ATIMP: BCMA/CD19 CAR T-cells
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT04795882