RecruitingNCT04809025

Comparation of Endoscopic Biopsy and Postoperative Specimen for the Molecular Diagnosis of Gastric Cancer


Sponsor

Fudan University

Enrollment

510 participants

Start Date

May 24, 2021

Study Type

OBSERVATIONAL

Conditions

Summary

This study aims to test the hypothesis that the diagnosis for histological type, histological grade, LAUREN type, HER-2 expression, MSI/dMMR status, and EBV status in gastric cancer is at least as reliable when performed on endoscopic biopsy specimens as on surgical resection specimens.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This study is comparing tumor tissue samples taken by endoscopy before surgery versus samples taken from the surgical specimen after stomach cancer surgery, to see whether both samples give the same molecular (genetic) information — which is important for selecting targeted therapies. **You may be eligible if...** - You are between 18 and 75 years old - You have been diagnosed with primary stomach adenocarcinoma (confirmed by biopsy within the past 12 months) - You are scheduled for stomach cancer surgery with intent to remove all cancer (R0 gastrectomy) **You may NOT be eligible if...** - You are pregnant or breastfeeding - You have previously received chemotherapy or radiation for this cancer - You have other serious conditions that prevent safe surgery Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEendoscopy

gastroscope

PROCEDURESurgery

radical gastrectomy


Locations(1)

Fudan University Shanghai Cancer Center

Shanghai, Shanghai Municipality, China

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NCT04809025


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