RecruitingPhase 4NCT04826237

Oral Statins and Protection From Hearing Loss

Towards a Self-Administered Hearing Protection Regimen


Sponsor

Northwestern University

Enrollment

100 participants

Start Date

Feb 9, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

A small clinical trial for idiopathic sudden sensorineural hearing loss (ISSNHL). Will the addition of an oral statin to the standard treatment (oral methylprednesolone and the salvage therapy of intratympanic dexamethasone) improve the treatment outcome for patients with ISSNHL? This study will compare the two treatments and quantitatively evaluate hearing and speech discrimination and have the patients subjectively evaluate tinnitus.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Placebo, a drug called Statin, and others for people with sudden sensorineural hearing loss. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 80 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGStatin

Oral dose to be taken with methylprednisolone

DRUGmethylprednisolone

oral dose, standard of care

DRUGdexamethasone

Drug for intratympanic administration

DRUGPlacebo

Capsule the same as for statins but without statin


Locations(1)

Northwestern Memorial Hospital

Chicago, Illinois, United States

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NCT04826237


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