Myocardial Ischemia Without Obstructive Coronary Stenoses
Myocardial Ischemia Without Obstructive Coronary Stenoses: A Prospective Observational Study With Invasive Coronary Pressure and Flow Measurements and Endothelial Function Test
Hospital San Carlos, Madrid
600 participants
Nov 8, 2017
OBSERVATIONAL
Conditions
Summary
Coronary-related myocardial ischemia can result from obstructive epicardial stenosis or non-obstructive causes including coronary microcirculatory dysfunction and vasomotor disorders. This prospective study has been created in order to provide knowledge in the field of non-obstructive coronary artery disease.
Eligibility
Inclusion Criteria3
- Written informed consent available.
- Age ≥ 18 years.
- Patient eligible for invasive physiological assessment with adenosine and / or acetylcholine.
Exclusion Criteria6
- Hemodynamic instability.
- Anticipated technical issues for physiology wire measurements.
- Culprit vessel of acute coronary syndrome
- Contraindications for adenosine administration.
- Contraindications for acetylcholine test.
- Reduced life expectancy (less than 1 year).
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Interventions
Coronary hemodynamics and vessel anatomical measures obtained during adenosine and acetylcholine evaluation with a dedicated physiology wire
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT04827498