Sustained Oral Fiber Supplementation for Patients Undergoing Donor Stem Cell Transplantation for Hematological Malignancies
Feasibility of Implementing Sustained Oral Fiber Supplementation for Patients Undergoing Allogeneic Hematopoietic Cell Transplantation for Hematological Malignancies
Fred Hutchinson Cancer Center
40 participants
Jun 22, 2022
INTERVENTIONAL
Conditions
Summary
This clinical trial examines sustained oral fiber supplementation for patients undergoing donor stem cell transplantation for hematological malignancies. Patients undergoing donor stem cell transplantation often develop oral and gastrointestinal damage from chemotherapy, radiotherapy, or graft-versus-host disease. Oral fiber nutrition support may improve overall nutrition, support a normal gut microbiome (bacteria that live in the gut) and/or improve gut function in patients undergoing stem cell transplants.
Eligibility
Plain Language Summary
Simplified for easier understanding
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
Given enteral nutrition via nasoenteric feeding
Given standard of care, which may be parenteral nutrition
Ancillary studies
Receive fiber supplementation orally or enterally
Undergo collection of blood and stool samples
Ancillary studies
Ancillary studies
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT04829136