Clinical Response and Toxicity of Hypo-fractionated Chemoradiotherapy in Cervix Cancer

This study is testing whether a shorter, more intense course of radiation (called hypofractionated chemoradiotherapy) works just as well as a longer standard course for treating cervical cancer. Fewer sessions could be more convenient and equally effective for patients. **You may be eligible if...** - You have been diagnosed with cervical cancer confirmed by pathology (squamous cell carcinoma, adenocarcinoma, or adenosquamous type) - Your cancer is at a stage eligible for definitive treatment with radiation and chemotherapy (FIGO stages IB–IIIC1 with certain conditions) - You are planned to receive chemoradiotherapy followed by brachytherapy (internal radiation) - Your kidneys function well enough to tolerate chemotherapy **You may NOT be eligible if...** - Your cancer is at a very early stage (IA) or has spread very far (stage IV) - Your kidneys are not functioning well enough (creatinine clearance below 30 ml/min) - You have inflammatory bowel disease or connective tissue disorders - You have had prior radiation to the pelvis - Your ECOG performance score is above 2 (meaning you are bedridden or too unwell) Talk to your doctor to see if this trial is right for you.