Impact of Peri-operative tEstosterone Levels on oNcological and Functional Outcomes in RadiCal prostatEctomy
Canisius-Wilhelmina Hospital
140 participants
Dec 12, 2022
INTERVENTIONAL
Conditions
Summary
Sexual dysfunction is a common side effect of radical prostatectomy (RP) and has a significant negative impact on quality of life. With age the testosterone level in men declines; around 30% of men over 70 years of age meet the criteria of testosterone deficiency (TD). The negative impact of both TD and RP on sexual performance are likely to add up. The aim of this study is to assess the efficacy and safety of testosterone replacement therapy (TRT) on functional and oncological outcomes in testosterone deficient men following RP for prostate cancer (PCa).
Eligibility
Plain Language Summary
Simplified for easier understanding
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Interventions
Topical gel containing testosterone
Topical gel without active substance
Locations(10)
View Full Details on ClinicalTrials.gov
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NCT04833426